Celebrating Over 20 Years Since Their Discovery

Salvestrols are the result of over two decades of dedicated scientific research. First developed around the turn of the century by leading UK researchers, these unique plant-based phytochemicals have been trusted by health-conscious individuals around the world for more than 20 years.

  • Discovery of CYP-1B1 Early 1990s

    Professor Dan Burke's research group at De Montfort University, Leicester (UK) discovered the enzyme CYP1B1 — a protein found almost exclusively in cancer cells and absent from healthy tissue.

  • Around the year 2000

    Professor Gerry Potter (Professor of Medicinal Chemistry, also at De Montfort University) discovered that certain plant-based phytochemicals are metabolised specifically by CYP1B1

  • 2005

    The "Salvestrol Concept" was formally developed and articulated. This milestone marked the transition from laboratory discovery to a recognised nutritional concept, paving the way for Salvestrols to be developed into the dietary supplements available today.

  • A New Era of Innovation (2020s)

    The 2020s brought a new range of specialised nesem-based products

    Moderaflam — formulated to support the body's natural inflammatory response

    Neurostrols — developed to support neurological health and cognitive well-being

    Lupostrols — bringing the benefits of Salvestrol science to pets

    These innovations reflect over two decades of growing research and a continued commitment to plant-based nutrition.

Naturally Elicited, Specifically Extracted Molecules

Stage one of this is the natural elicitation of active phyto molecules, These are the result of a natural mechanism within the plant (natural elicitation), which allows the plant to respond to environmental circumstances by producing elicited secondary plant metabolites.

Stage two is to “ SPECIFICALLY EXTRACT” the molecules of interest in a non-damaging, natural way. To this end we delpoy advanced technology (Liquid chromatography–mass spectrometry or LC-MS) to identify and then extract these naturally elicited molecules that form the basis of all of our unique products.

NESEM® represents our unique and science-based technology for the phyto-actives used in our product range.

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